Name Date shares traded shares held Price type (sell/buy) option BRENNER LOUIS MD 11/14/2021 40,328.00 288,576.00 0.81 Sell No BRENNER LOUIS MD 11/14/2021 125,582.00 328,904.00 n/a Buy No BRENNER LOUIS MD 05/09/2021 25,215.00 203,322.00 1.11 Sell No BRENNER LOUIS MD 05/09/2021 83,721.00 228,537.00 n/a Buy No WHOLIHAN EDWARD 12/16/2020 68,550.00 121,272.00 1.36 Sell No BRENNER LOUIS MD 12/16/2020 103,116.00 144,816.00 1.36 Sell No WHOLIHAN EDWARD 12/16/2020 164,822.00 189,822.00 n/a Buy No BRENNER LOUIS MD 12/16/2020 247,932.00 247,932.00 n/a Buy No WHOLIHAN EDWARD 05/08/2018 25,000.00 25,000.00 1.59 Buy No HBM BioCapital II LP 11/05/2017 71,428.00 1,638,330.00 14.00 Buy No HBM BioCapital II LP 11/05/2017 140,841.00 1,566,902.00 n/a Buy No HBM BioCapital II LP 11/05/2017 1,426,061.00 1,426,061.00 n/a Buy No FHM VI, L.L.C. 11/05/2017 500,000.00 3,330,373.00 14.00 Buy No FHM VI, L.L.C. 11/05/2017 2,830,373.00 2,830,373.00 n/a Buy No Hadley Harbor Master Investors (Cayman) L.P. 11/05/2017 757,684.00 757,684.00 n/a Buy No Third Rock Ventures III, L.P. 11/05/2017 215,000.00 2,790,964.00 14.00 Buy No Third Rock Ventures III, L.P. 11/05/2017 2,575,964.00 2,575,964.00 n/a Buy No Kraus Stephen 11/05/2017 0.00 n/a n/a Buy No Kraus Stephen 11/05/2017 0.00 n/a n/a Buy No TEPPER ROBERT I 11/05/2017 215,000.00 2,790,964.00 14.00 Buy No TEPPER ROBERT I 11/05/2017 2,575,964.00 2,575,964.00 n/a Buy No Bessemer Venture Partners VII L.P. 11/05/2017 36,000.00 2,263,365.00 14.00 Buy No Bessemer Venture Partners VII L.P. 11/05/2017 2,227,365.00 2,227,365.00 n/a Buy No Topper James N 11/05/2017 500,000.00 3,330,373.00 14.00 Buy No Topper James N 11/05/2017 254,409.00 2,830,373.00 n/a Buy No https://www-allenapharma-com.translate.goog/...hl=de&_x_tr_pto=sc |