Richtung USA verkaufen, machen die Pharmas Fortschritt um Fortschritt mit ihren HuCAL-Projekten. Endlich ist die Studie beendet! A Multiple Ascending Dose Study of R1450 in Patients With Alzheimer Disease.
This study has been completed. First Received: September 18, 2007 Last Updated: November 17, 2009 History of Changes Sponsor: Hoffmann-La Roche Information provided by: Hoffmann-La Roche ClinicalTrials.gov Identifier: NCT00531804
Purpose This study will evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of R1450 in patients with mild to moderate Alzheimer Disease. Patients will be randomized to receive either R1450 or placebo by intravenous infusion for a total of 7 doses. The starting dose will be escalated in subsequent cohorts of patients in an adaptive manner, after a satisfactory assessment of safety, tolerability and pharmacokinetics of the previous dose. The anticipated time on study treatment is 3-12 months, and the target sample size is <100 individuals.
Condition Intervention Phase Alzheimer Disease Drug: R1450 Phase I
Study Type: Interventional Study Design: Treatment, Randomized, Double Blind (Subject, Investigator), Parallel Assignment, Safety Study Official Title: A Multi-center, Multiple-ascending Dose, Randomized, Double-blind, Placebo-controlled, Parallel-group Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of RO4909832 Following Intravenous Infusion in AD Patients
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Bin ja gespannt, ob Roche auch mal Ergebnisse veröffentlicht oder ob wir nur indirekt von der erfolgreichen P1 überzeugt werden, weil Roche die P2 starten wird?
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